Acrylamide (or
acrylic
amide) is a potentially dangerous
chemical compound with the
chemical formula C3H5NO. Its
IUPAC name is
2-propenamide. It is a white odourless
crystalline solid, soluble in
water,
ethanol,
ether and
chloroform. Acrylamide is incompatible with acids, bases, oxidizing agents, iron and iron salts. It decomposes non-thermally to form
ammonia, and thermal decomposition produces
carbon monoxide,
carbon dioxide, and oxides of
nitrogen.
Acrylamide is prepared on an industrial scale by the hydrolysis of
acrylonitrile by
nitrile hydratase.
Most acrylamide is used to synthesize
polyacrylamides, which find many uses as water-soluble
thickeners. These include use in
wastewater treatment,
gel electrophoresis (
SDS-PAGE),
papermaking,
ore processing, and the manufacture of
permanent press fabrics. Some acrylamide is used in the manufacture of
dyes and the manufacture of other
monomers.
Acrylamide also occurs in many cooked starchy foods. Acrylamide was accidentally discovered in foods in April 2002 by scientists in Sweden when they found the chemical in
starchy foods, such as
potato chips,
French fries and bread that had been heated (production of acrylamide in the heating process was shown to be temperature-dependent). It was not found in food that had been boiled nor in foods that were not heated. In December 2009, after a positive reception from the food industry, Health Canada invited comment from the public on this proposal.
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